Penelope E. Stein

Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria

Manisha Balwani, Eliane Sardh, Paolo Ventura et al. · New England Journal of Medicine · 2020 · 562 citations · Full text

Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease

Keren Carss, Gavin Arno, Marie Erwood et al. · The American Journal of Human Genetics · 2016 · 463 citations · Full text

Whole-genome Sequencing, Allelic Variant, Genetic Disorder +11

Crystal structure of uncleaved ovalbumin at 1·95 Å resolution

Penelope E. Stein, Andrew G. W. Leslie, J.T. Finch et al. · Journal of Molecular Biology · 1991 · 426 citations

Crystal Structure, Structural Biology, Medicine +4

Hormone binding globulins undergo serpin conformational change in inflammation

Philip A. Pemberton, Penelope E. Stein, Mark B. Pepys et al. · Nature · 1988 · 418 citations

Protein Function, Signal Transduction, G Protein-coupled Receptor +7

Crystal structure of ovalbumin as a model for the reactive centre of serpins

Penelope E. Stein, Andrew G. W. Leslie, J.T. Finch et al. · Nature · 1990 · 393 citations

Crystal Structure, Protein Folding, Protein X-ray Crystallography +9