Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

Fabienne Guillaumond, Ghislain Bidaut, Mehdi Ouaïssi, +19

Proceedings of the National Academy of Sciences

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

Fabienne Guillaumond, Julie Leca, O. Porta Olivares, +10

Proceedings of the National Academy of Sciences

Synthesis and antifungal activity of cholesterol-hydrazone derivatives

Céline Loncle, Jean Michel Brunel, Nicolas Vidal, +2

European Journal of Medicinal Chemistry

Antifungal AgentPharmacologyPharmaceutical ChemistryCholesterol-hydrazone DerivativesNatural Product Synthesis

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness

Julie Leca, Sébastien Martinez, Sophie Lac, +20

Journal of Clinical Investigation

PathologyExtracellular MicrovesiclesComplex FormationCancer BiologyTumor Biology +15

Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts

Rémy Nicolle, Yuna Blum, Laëtitia Marisa, +38

Cell Reports

IL17 Functions through the Novel REG3β–JAK2–STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer

Céline Loncle, Laia Bonjoch, Emma Folch‐Puy, +10

Cancer Research

ImmunologyImmune RegulationPathologyInnate ImmunityCancer Biology +19

Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer

Juan Liu, Chao Chen, Tuo Wei, +12

Exploration

Homotypic cell cannibalism, a cell‐death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer

Carla E. Cano, María José Sandí, Tewfik Hamidi, +10

EMBO Molecular Medicine

Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the <scp>BET</scp> bromodomain inhibitor <scp>JQ</scp> 1: implications for individualized medicine efforts

Benjamin Bian, Martin Bigonnet, Odile Gayet, +25

EMBO Molecular Medicine

Squalamine: An Appropriate Strategy against the Emergence of Multidrug Resistant Gram-Negative Bacteria?

Chanaz Salmi, Céline Loncle, Nicolas Vidal, +6

PLoS ONE

Antimicrobial SusceptibilityAppropriate StrategyAntibioticsMicrobial PathogensBiochemistry +13