Liver X Receptor (LXR)-β Regulation in LXRα-Deficient Mice: Implications for Therapeutic Targeting

Elaine Quinet, Dawn Savio, Anita Halpern, +5

Molecular Pharmacology

Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

Elaine Quinet, Dawn Savio, Anita Halpern, +3

Journal of Lipid Research

Characterization of a Calcium-Activated Chloride Channel as a Shared Target of Th2 Cytokine Pathways and Its Potential Involvement in Asthma

Yuhong Zhou, Qu Dong, Jamila Louahed, +7

American Journal of Respiratory Cell and Molecular Biology

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyImmunologic Mechanism +16

Synergistic Regulation of the Human Interleukin-12 p40 Promoter by NFκB and Ets Transcription Factors in Epstein-Barr Virus-transformed B Cells and Macrophages

Giorgia Gri, Dawn Savio, Giorgio Trinchieri, +1

Journal of Biological Chemistry

Modulation of Adipose Tissue Development by Pharmacological Inhibition of PAI-1

David L. Crandall, Elaine Quinet, Soulaf El Ayachi, +5

Arteriosclerosis Thrombosis and Vascular Biology

A Calcium‐Activated Chloride Channel Blocker Inhibits Goblet Cell Metaplasia and Mucus Overproduction

Yuhong Zhou, Michael D. Shapiro, Qu Dong, +11

Novartis Foundation symposium

Inflammatory Lung DiseaseLung InflammationImmunologyImmunologic MechanismHclca1 Expression +17

Discovery of Phenyl Acetic Acid Substituted Quinolines as Novel Liver X Receptor Agonists for the Treatment of Atherosclerosis

Baihua Hu, Michael D. Collini, Rayomand J. Unwalla, +21

Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ChemistryPharmaceutical ScienceQuinolines 15Biochemistry +12

Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

Elizabeth A. DiBlasio-Smith, Maya Arai, Elaine Quinet, +16

Journal of Translational Medicine

Further modification on phenyl acetic acid based quinolines as liver X receptor modulators

Baihua Hu, James W. Jetter, David H. Kaufman, +18

Bioorganic & Medicinal Chemistry

Molecular PharmacologyBiochemistryFunctional SelectivityMedicineLiver Physiology +8

Carboxylic acid based quinolines as liver X receptor modulators that have LXRβ receptor binding selectivity

Baihua Hu, Elaine Quinet, Rayomand J. Unwalla, +11

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyCarboxylic AcidBiochemistryG Protein-coupled ReceptorMedicine +5