Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

Molecular Physiology, Signal Transduction, Signaling Pathway +8

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

Angela Brooks‐Wilson, Michel Marcil, Susanne M. Clee et al. · Nature Genetics · 1999 · 1.7K citations

Mendelian Disorder, Disease Mechanism, Genetic Disorder +13

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development · 2000 · 1.7K citations · Full text

Oxysterol Receptors, Sterol Sensors, Transcriptional Regulation +16

Role of LXRs in control of lipogenesis

Joshua R. Schultz, Hua Tu, Alvin Luk et al. · Genes & Development · 2000 · 1.7K citations · Full text

Cell Culture, Lipid Movement, Cellular Physiology +19

Accumulation of Dietary Cholesterol in Sitosterolemia Caused by Mutations in Adjacent ABC Transporters

Knut Erik Berge, Hui Tian, Gregory A. Graf et al. · Science · 2000 · 1.6K citations