Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Mohsen Malehmir, Dominik Pfister, Suchira Gallage, +64

Nature Medicine

HepatologyMedicineLiver PhysiologyPlatelet GpibαSubsequent Liver Cancer +7

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

Carsten Deppermann, Deya Cherpokova, Paquita Nurden, +13

Journal of Clinical Investigation

ImmunologyBlood CellPlatelet PathobiologyGray Platelet SyndromeMajor Platelet Organelles +19

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection

Peter Kraft, Eva Göb, Michael K. Schuhmann, +11

Stroke

Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

Justin Deniset, Darrell D. Belke, Woo‐Yong Lee, +14

Immunity

Primordial GATA6 macrophages function as extravascular platelets in sterile injury

Joël Zindel, Moritz Peiseler, Mokarram Hossain, +8

Science

α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

Bas G. J. Surewaard, Ajitha Thanabalasuriar, Zhutian Zeng, +11

Cell Host & Microbe

InflammationMicrobial ToxinLiver InjuryPathogenesisPathology +2

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

Carsten Deppermann, Rachel M. Kratofil, Moritz Peiseler, +8

The Journal of Experimental Medicine

Functional Platelet CompartmentImmunologyBlood CellPathologyCell Death +19

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

Kate L. Lowe, Brenda Finney, Carsten Deppermann, +8

Blood

Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation

Hanna Englert, Chandini Rangaswamy, Carsten Deppermann, +17

EBioMedicine

Inhibition of Platelet GPVI Protects Against Myocardial Ischemia–Reperfusion Injury

Christina Pachel, Denise Mathes, Paula-Anahi Arias-Loza, +7

Arteriosclerosis Thrombosis and Vascular Biology