Advances in process monitoring tools for cell culture bioprocesses

Liang Zhao, Hsu‐Yuan Fu, Weichang Zhou, +1

Engineering in Life Sciences

EngineeringAnalytical MicrosystemsCell CultureBiomedical EngineeringBioprocess Engineering +18

Recurring genomic structural variation leads to clonal instability and loss of productivity

Arpan Bandyopadhyay, Sofie A. O’Brien, Liang Zhao, +3

Biotechnology and Bioengineering

CytogeneticsGeneticsGenomic MechanismGenomicsClonal Instability +18

Serum-Free Suspension Culture of MDCK Cells for Production of Influenza H1N1 Vaccines

Huang Ding, Peng Wen-Juan, Qian Ye, +12

PLoS ONE

Suspension CellsImmunologyImmunodominanceCell CultureFlu Vaccination +15

Identification of multiple sources of the acidic charge variants in an IgG1 monoclonal antibody

Shiwei Miao, Panpan Xie, Mao Zou, +7

Applied Microbiology and Biotechnology

ImmunohematologyImmunocytochemical TechniqueAutoimmune DiseaseMultiple SourcesMedicine +13

The combined effect of sodium butyrate and low culture temperature on the production, sialylation, and biological activity of an antibody produced in CHO cells

Fei Chen, Tian-Ci Kou, Fan Li, +4

Biotechnology and Bioprocess Engineering

Immunocytochemical TechniqueBiochemistryMedicineGlycobiologyImmunology +6

Detailed understanding of enhanced specific productivity in Chinese hamster ovary cells at low culture temperature

Tian-Ci Kou, Fan Li, Yan Zhou, +4

Journal of Bioscience and Bioengineering

OocyteLow Culture TemperatureFertilityCell DivisionEnhanced Specific Productivity +9

Physicochemical and Biological Characterization of the Proposed Biosimilar Tocilizumab

Shiwei Miao, Li Fan, Liang Zhao, +4

BioMed Research International

Medicinal ChemistryProtein FunctionOriginator TocilizumabBiochemistryNatural Sciences +12

Model-Driven Engineering of N-Linked Glycosylation in Chinese Hamster Ovary Cells

Christopher S. Stach, Meghan G. McCann, Conor M. O’Brien, +9

ACS Synthetic Biology

EngineeringGlycobiologyMolecular BiologySynthetic CircuitPolysaccharide +22

Pathway Network Analysis of Complex Diseases Based on Multiple Biological Networks

Fang Zheng, Wei Le, Liang Zhao, +1

BioMed Research International

EngineeringAlternative DatasetGeneticsBreast Cancer DatasetInteraction Network +20

Biocatalytic resolution of nitro-substituted phenoxypropylene oxides with Trichosporon loubierii epoxide hydrolase and prediction of their enantiopurity variation with reaction time

Yi Xu, Jian‐He Xu, Jiang Pan, +2

Journal of Molecular Catalysis B Enzymatic

Chemical EngineeringEngineeringEnzyme CatalysisBiocatalysisBiochemical Engineering +7