Tomomi Noguchi‐Yachide

Synthesis and evaluation of novel dual BRD4/HDAC inhibitors

Seika Amemiya, Takao Yamaguchi, Yuichi Hashimoto et al. · Bioorganic & Medicinal Chemistry · 2017 · 60 citations · Full text

Medicinal Chemistry, Medicine, Drug Development +3

Design, Synthesis, and Biological Evaluation of Novel Transrepression-Selective Liver X Receptor (LXR) Ligands with 5,11-Dihydro-5-methyl-11-methylene-6<i>H</i>-dibenz[<i>b</i>,<i>e</i>]azepin-6-one Skeleton

Atsushi Aoyama, Kaori Endo‐Umeda, Kenji Kishida et al. · Journal of Medicinal Chemistry · 2012 · 58 citations · Full text

Drug Target, Cellular Pharmacology, Systems Pharmacology +19

Separation of α-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRα-selective antagonists

Kazunori Motoshima, Tomomi Noguchi‐Yachide, Kazuyuki Sugita et al. · Bioorganic & Medicinal Chemistry · 2009 · 48 citations · Full text

Lxrα-selective Antagonists, Pharmaceutical Science, Biochemistry +8

Antiproliferative and apoptosis-inducing activities of alkyl gallate and gallamide derivatives related to (−)-epigallocatechin gallate

Kosuke Dodo, Taro Minato, Tomomi Noguchi‐Yachide et al. · Bioorganic & Medicinal Chemistry · 2008 · 47 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +7

β-Naphthoflavone analogs as potent and soluble aryl hydrocarbon receptor agonists: Improvement of solubility by disruption of molecular planarity

Yuji Fujita, Mitsuhiro Yonehara, Masashi Tetsuhashi et al. · Bioorganic & Medicinal Chemistry · 2009 · 42 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +10