Annabel L. Cutter

Polyketide synthesis in vitro on a modular polyketide synthase

Kirsten E. H. Wiesmann, Jesús Cortés, Murray J. B. Brown et al. · Chemistry & Biology · 1995 · 86 citations · Full text

Biosynthesis, Engineering, Biocatalysis +6

Evaluating precursor-directed biosynthesis towards novel erythromycins through in vitro studies on a bimodular polyketide synthase

Kira J. Weissman, Annabel L. Cutter, Ulf Hanefeld et al. · Chemistry & Biology · 1998 · 47 citations · Full text

Biosynthesis, Engineering, Biotransformation +7

A mutant generated by expression of an engineered DEBS 1 protein from the erythromycin-producing polyketide synthase (PKS) in Streptomyces coelicolor produces the triketide as a lactone, but the major product is the nor-analogue derived from acetate as starter acid

Murray J. B. Brown, Jesús Cortés, Annabel L. Cutter et al. · Journal of the Chemical Society Chemical Communications · 1995 · 39 citations

Engineering, Molecular Biology, Biosynthesis +17

Enantiospecific Synthesis of Analogues of the Diketide Intermediate of the Erythromycin Polyketide Synthase (PKS)

Rebecca Harris, Annabel L. Cutter, Kira J. Weissman et al. · Journal of Chemical Research Synopses · 1998 · 16 citations

Substrate Selectivity, Bioorganic Chemistry, Activated Derivatives +19