Anke Jakobs

Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

Sagar Uttarkar, Emilie Dassé, Anna Coulibaly et al. · Blood · 2015 · 99 citations · Full text

Medicine, Oncology, Pharmacology +11

Monensin, a novel potent MYB inhibitor, suppresses proliferation of acute myeloid leukemia and adenoid cystic carcinoma cells

Maria V. Yusenko, Amke Trentmann, Mattias K. Andersson et al. · Cancer Letters · 2020 · 63 citations

Medicine, Oncology, Pharmacology +7

Helenalin Acetate, a Natural Sesquiterpene Lactone with Anti-inflammatory and Anti-cancer Activity, Disrupts the Cooperation of CCAAT Box/Enhancer-binding Protein β (C/EBPβ) and Co-activator p300

Anke Jakobs, Simone Steinmann, Sarah Marie Henrich et al. · Journal of Biological Chemistry · 2016 · 42 citations · Full text

Medicine, Oncology, Pharmacology +15

The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression

Anna Coulibaly, Astrid Haas, Simone Steinmann et al. · PLoS ONE · 2018 · 29 citations · Full text

Medicine, Oncology, Pharmacology +12

Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ

Kim D. Falkenberg, Anke Jakobs, Julian C. J. Matern et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2017 · 26 citations

Medicine, Oncology, Pharmacology +10