The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a

Liang Liu, Xueyan Li, Jun Ma, +6

Cell

Rna-guided Rna CleavageNatural SciencesRna Structure PredictionRna BiologyMolecular Biology +4

Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities

Liang Liu, Xueyan Li, Jiuyu Wang, +6

Cell

BiochemistryNatural SciencesRna Structure PredictionC2c2 Rnase ActivitiesRna Biology +3

C2c1-sgRNA Complex Structure Reveals RNA-Guided DNA Cleavage Mechanism

Liang Liu, Peng Chen, Min Wang, +4

Molecular Cell

Natural SciencesC2c1-sgrna Complex StructureRna BiologyMolecular BiologyGene Expression

Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference

Lilan You, Jun Ma, Jiuyu Wang, +7

Cell

Co-transcriptional InterferenceChromatinTranscriptional RegulationChromatin StructureStructure Studies +10

Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States

Wei Sun, Jing Yang, Zhi Cheng, +14

Molecular Cell

MedicineMolecular BiologyGene EditingGenome EditingMicrobiology +5

A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment

Xiao Zhao, Liang Liu, Jiayan Lang, +6

Cancer Letters

Tumor BiologyPancreatic CancerGenome SurgeryMutant KrasCrispr-cas13a System +9

Gut Microbe Analysis Between Hyperthyroid and Healthy Individuals

Lei Zhou, Xinli Li, Ayaz Ahmed, +6

Current Microbiology

NutritionHealthy IndividualsPhysiologyGut MicrobiologyPathology +7

Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race

Liang Liu, Maolu Yin, Min Wang, +1

Molecular Cell

Off-target EffectGeneticsMolecular BiologyGenetic EngineeringStructural Basis +7

Mouse γ-Synuclein Promoter-Mediated Gene Expression and Editing in Mammalian Retinal Ganglion Cells

Qizhao Wang, Pei Zhuang, Haoliang Huang, +13

Journal of Neuroscience

<scp> <i>LTP3</i> </scp> contributes to disease susceptibility in <scp> <i>A</i> </scp> <i>rabidopsis</i> by enhancing abscisic acid ( <scp>ABA</scp> ) biosynthesis

Shan Gao, Wenya Guo, Wen Feng, +7

Molecular Plant Pathology