Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder

Shusuke Numata, Ikuo Otsuka, Tadasu Horai, +4

Translational Psychiatry

Epigenetic clock analysis of blood samples from Japanese schizophrenia patients

Ikuo Otsuka, Shusuke Numata, Tadasu Horai, +5

Schizophrenia

AgingEpigenetic ChangeGeneticsGenetic EpidemiologyEpidemiology Of Aging +17

Prescription patterns in patients with schizophrenia in Japan: First‐quality indicator data from the survey of “Effectiveness of Guidelines for Dissemination and Education in psychiatric treatment (EGUIDE)” project

Kayo Ichihashi, Hikaru Hori, Naomi Hasegawa, +33

Neuropsychopharmacology Reports

Loss of chromosome Y in blood, but not in brain, of suicide completers

Atsushi Kimura, Akitoyo Hishimoto, Ikuo Otsuka, +7

PLoS ONE

Chemokine alterations in the postmortem brains of suicide completers

Yutaka Shinko, Ikuo Otsuka, Tadasu Horai, +5

Journal of Psychiatric Research

Suicide CompletersNeuroanatomyMedicineBrain InjuryNeurology +8

Epigenetic clock analysis reveals increased plasma cystatin C levels based on DNA methylation in major depressive disorder

Takaki Tanifuji, Ikuo Otsuka, Kentaro Mouri, +4

Psychiatry Research

ChromatinPsychiatryEpigenetic ChangeGeneticsDna Methylation +8

Accelerated extrinsic epigenetic aging and increased natural killer cells in blood of suicide completers

Ikuo Otsuka, Tadasu Horai, Takashi Hirata, +5

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Suicide CompletersChromatinAgingLongevityEpigenetic Change +10

Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder

Keita Idemoto, Tamaki Ishima, Tomihisa Niitsu, +20

Journal of Psychiatric Research

PsychiatryMood SymptomHematologyDepressionMajor Depressive Disorder +8

Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder

Ryota Shindo, Takaki Tanifuji, Ikuo Otsuka, +4

npj Aging

Investigation of chromosome Y loss in men with schizophrenia

Takashi Hirata, Akitoyo Hishimoto, Ikuo Otsuka, +4

Neuropsychiatric Disease and Treatment