Mapping human microbiome drug metabolism by gut bacteria and their genes

Michael Zimmermann, Maria Zimmermann‐Kogadeeva, Rebekka Wegmann, +1

Nature

ProbioticDysbiosisGut BacteriaHealth SciencesMedicine +9

Separating host and microbiome contributions to drug pharmacokinetics and toxicity

Michael Zimmermann, Maria Zimmermann‐Kogadeeva, Rebekka Wegmann, +1

Science

DysbiosisMetabolomic ProfilingGut MicrobiotaBrivudine Drug MetabolismDrug Resistance +15

European summer climate variability in a heterogeneous multi-model ensemble

Pier Luigi Vidale, Daniel Lüthi, Rebekka Wegmann, +1

Climatic Change

ClimatologyEarth ScienceEngineeringClimate ForecastingClimate Modeling +4

The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support

Anja Irmisch, Ximena Bonilla, Stéphane Chevrier, +23

Cancer Cell

Tumor BiologyTumor HeterogeneityMedicineFunctional TumorPathology +10

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

Rebekka Wegmann, Marilisa Neri, Sven Schuierer, +11

Genome biology

GeneticsGenomicsSingle Cell SequencingMethodology GapStem Cells +17

SCIM: universal single-cell matching with unpaired feature sets

Stefan G. Stark, Joanna Ficek, Francesco Locatello, +120

Bioinformatics

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity

Sohyon Lee, Marcel Bühler, Julien Mena, +21

Nature Medicine

Establishing standardized immune phenotyping of metastatic melanoma by digital pathology

Bettina Sobottka, Marta Nowak, Anja Frei, +117

Laboratory Investigation

Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer

Arthur Dondi, Ulrike Lischetti, Francis Jacob, +129

Nature Communications

Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma

Klara Kropivšek, Paul Kachel, Sandra Goetze, +11

Nature Cancer