TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis

Yves Chicheportiche, P Bourdon, Haoda Xu, +5

Journal of Biological Chemistry

Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

Zhulun Wang, G Benoît, Jinsong Liu, +6

Nature

Signal TransductionG Protein-coupled ReceptorHormonal ReceptorFunctional SelectivityReceptor (Biochemistry) +6

Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction

Xiaoqi Chen, David J. Kopecky, Jeff Mihalic, +17

Journal of Medicinal Chemistry

Molecular BiologyChemical BiologyProtein SynthesisTranslational PharmacologyCompound 33 +15

Molecular Basis of Sphingosine Kinase 1 Substrate Recognition and Catalysis

Zhulun Wang, Xiaoshan Min, Shou-Hua Xiao, +9

Structure

Signal TransductionSphingosine Kinase 1BiochemistryNatural SciencesReceptor Tyrosine Kinase +4

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo

Alykhan Motani, Zhulun Wang, Marion Conn, +14

Journal of Biological Chemistry

Rbp4 LoweringRetinal TherapiesInsulin SignalingMetabolic SyndromeRetina +14

T2384, a Novel Antidiabetic Agent with Unique Peroxisome Proliferator-activated Receptor γ Binding Properties

Yang Li, Zhulun Wang, Noboru Furukawa, +12

Journal of Biological Chemistry

Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)

Xiaoshan Min, Stephen T. Thibault, Amy C. Porter, +11

Proceedings of the National Academy of Sciences

Distinctive molecular inhibition mechanisms for selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1

Hua Tu, Jay P. Powers, Jinsong Liu, +13

Bioorganic & Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicineMechanism Of ActionSelective Inhibitors +5

Structural Characterization and Pharmacodynamic Effects of an Orally Active 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor

Clarence Hale, Murielle M. Véniant, Zhulun Wang, +11

Chemical Biology & Drug Design

Structural CharacterizationAldo-keto ReductaseDehydrogenase Type 1PharmacotherapyChemical Biology +15

Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4

Yingcai Wang, Richard Connors, Pingchen Fan, +16

Bioorganic & Medicinal Chemistry Letters

Protein AssemblyBiochemistryMedicineNatural SciencesMolecular Biology +8