Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design

S. K. Sharma, Natalia de Val, Shridhar Bale, +6

Cell Reports

Human RetrovirusImmunologyAntiviral ResponseVirologyVaccine Design +4

Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase

Abhishek Chatterjee, Nalin Abeydeera, Shridhar Bale, +5

Nature

BiosynthesisBiochemistryNatural SciencesMolecular BiologyYeast

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

Viktoriya Dubrovskaya, Karen Tran, Gabriel Ozorowski, +25

Immunity

A shared structural solution for neutralizing ebolaviruses

João M. Dias, Ana I. Kuehne, Dafna M. Abelson, +11

Nature Structural & Molecular Biology

Virus StructureVirologyMicrobiologyVirus-host InteractionViral Structural Protein +2

Crystal Structure and Mechanism of Tryptophan 2,3-Dioxygenase, a Heme Enzyme Involved in Tryptophan Catabolism and in Quinolinate Biosynthesis^,

Yang Zhang, Seong A. Kang, Tathagata Mukherjee, +4

Biochemistry

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

Zachary A. Bornholdt, Esther Ndungo, Marnie L. Fusco, +5

mBio

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

Paola Martinez-Murillo, Karen Tran, Javier Guenaga, +16

Immunity

Particulate ArrayHuman RetrovirusImmunologyAntiviral ResponseVirology +3

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

Shridhar Bale, Jean‐Philippe Julien, Zachary A. Bornholdt, +9

PLoS Pathogens

Crystal StructureViral ReplicationInterferon AntagonismImmunologyMolecular Biology +14

Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies

Yu Feng, Karen Tran, Shridhar Bale, +8

PLoS Pathogens

Neutralizing AntibodiesImmunologyAntiviral DrugImmunotherapyViral Persistence +15

Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses

Shridhar Bale, Geraldine Goebrecht, Armando Stano, +6

Journal of Virology