Ethacrynic Acid Butyl-Ester Induces Apoptosis in Leukemia Cells through a Hydrogen Peroxide–Mediated Pathway Independent of Glutathione<i>S</i>-Transferase P1-1 Inhibition

Rui Wang, Chunmin Li, Dandan Song, +3

Cancer Research

Novel Oxadiazole Analogues Derived from Ethacrynic Acid: Design, Synthesis, and Structure−Activity Relationships in Inhibiting the Activity of Glutathione <i>S</i>-Transferase P1-1 and Cancer Cell Proliferation

Xinmei Yang, Guyue Liu, Hongcai Li, +8

Journal of Medicinal Chemistry

Synthesis and structure–activity relationship of ethacrynic acid analogues on glutathione-s-transferase P1-1 activity inhibition

Guisen Zhao, Tao Yu, Rui Wang, +2

Bioorganic & Medicinal Chemistry

Structure–activity RelationshipMedicinal ChemistryBiochemistryEthacrynic Acid AnaloguesNatural Sciences +6

Estrogen‐induced morphological and immunohistochemical changes in stroma and epithelium of rat ventral prostate

Guisen Zhao, PM Holterhus, Irmgard Dammshäuser, +2

The Prostate

Ethacrynic Acid and a Derivative Enhance Apoptosis in Arsenic Trioxide–Treated Myeloid Leukemia and Lymphoma Cells: The Role of Glutathione S-Transferase P1-1

Rui Wang, Changda Liu, Lijuan Xia, +4

Clinical Cancer Research

Discovery of novel pyrazole derivatives as potential anticancer agents in MCL

Fansheng Ran, Yang Liu, Daoguang Zhang, +2

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryNovel Pyrazole DerivativesMedicineDrug DiscoveryRational Drug Design +7

Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester

Peng Wang, Chuan Liu, Tino Sanches, +5

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicine +8

An overview of the functions of p53 and drugs acting either on wild- or mutant-type p53

Yongmi Huang, Zhihao Jiao, Yuqing Fu, +7

European Journal of Medicinal Chemistry

Molecular PharmacologyOncogenic AgentMolecular BiologyAnti-cancer AgentTumor Suppressor +4

Design and synthesis of novel 1-substituted 3-(6-phenoxypyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine analogs as selective BTK inhibitors for the treatment of mantle cell lymphoma

Fansheng Ran, Yang Liu, Shengping Yu, +4

Bioorganic Chemistry

Medicinal ChemistryMantle Cell LymphomaMedicineDrug DiscoveryPharmacological Agent +8

The synthesis of α,β-unsaturated carbonyl derivatives with the ability to inhibit both glutathione S-transferase P1-1 activity and the proliferation of leukemia cells

Guisen Zhao, Chuan Liu, Rui Wang, +4

Bioorganic & Medicinal Chemistry

BiosynthesisBiochemistryS-transferase P1-1 Activityβ-Unsaturated Carbonyl DerivativesLeukemia Cells +3