Douglas J. Swartz

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Andrew B. Ward, Paul Szewczyk, Vinciane Grimard et al. · Proceedings of the National Academy of Sciences · 2013 · 254 citations · Full text

Proteinlipid Interaction, Mouse P-gp, Protein Assembly +21

A Gene Optimization Strategy that Enhances Production of Fully Functional P-Glycoprotein in Pichia pastoris

Jiangping Bai, Douglas J. Swartz, Irina I. Protasevich et al. · PLoS ONE · 2011 · 107 citations · Full text

Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer–associated P-glycoprotein during ATP hydrolysis

Maria E. Zoghbi, Leo Mok, Douglas J. Swartz et al. · Journal of Biological Chemistry · 2017 · 70 citations · Full text

Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function

Zhengrong Yang, Qingxian Zhou, Leo Mok et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2016 · 18 citations · Full text

Protein Chemistry, Solution Structure, Biochemistry +10

P-glycoprotein is fully active after multiple tryptophan substitutions

Douglas J. Swartz, Joachim Weber, Ina L. Urbatsch · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2012 · 16 citations · Full text

Multiple Tryptophan Substitutions, Protein Function, Biochemistry +2