PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing

Gue‐Ho Hwang, You Kyeong Jeong, Omer Habib, +4

Nucleic Acids Research

Comprehensive analysis of prime editing outcomes in human embryonic stem cells

Omer Habib, Gizem Habib, Gue‐Ho Hwang, +1

Nucleic Acids Research

EngineeringIn Vivo Gene TherapyGeneticsAdult Stem CellPrime Editor +30

Role of mitochondrial fission-related genes in mitochondrial morphology and energy metabolism in mouse embryonic stem cells

Bong Jong Seo, Joonhyuk Choi, Hyeonwoo La, +4

Redox Biology

Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

Bipasha Mukherjee-Clavin, Ruifa Mi, Barbara Kern, +17

Nature Biomedical Engineering

Genetic DiseasesSystems BiologyMendelian DisorderGenetic DisorderPathology +5

Large DNA deletions occur during DNA repair at 20-fold lower frequency for base editors and prime editors than for Cas9 nucleases

Gue‐Ho Hwang, Seok‐Hoon Lee, Minsik Oh, +8

Nature Biomedical Engineering

DNA-dependent RNA cleavage by the Natronobacterium gregoryi Argonaute

Sunghyeok Ye, Taegeun Bae, Kyoungmi Kim, +6

Natronobacterium GregoryiMolecular BiologyMolecular GeneticsDna-dependent Rna CleavageGenome Engineering +14

Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells

Kwang Bo Jung, Ohman Kwon, Mi‐Ok Lee, +8

Journal of Clinical Medicine

Adult Stem CellStat3 KnockoutIntestinal OrganoidsEmbryologyInflammation +15

Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing

Annie Kim, Kun‐Gu Lee, Yeongbeen Kwon, +8

Stem Cell Reviews and Reports

HistocompatibilityHlaEngineeringGeneticsImmunology +21

A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting

Sojung Kim, Omer Habib, Jin‐Soo Kim, +3

Stem Cell Research

An improved method for the derivation of high quality iPSCs in the absence of c-Myc

Omer Habib, Gizem Habib, Hyun Woo Choi, +4

Experimental Cell Research

Electrical EngineeringImproved MethodEngineeringComputer EngineeringHigh Quality Ipscs