Laura M. Hagenah

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT

Jonathan Kim, Yong Zi Tan, Kathryn J. Wicht et al. · Nature · 2019 · 195 citations · Full text

Drug Resistance Analysis, Biochemistry, Antiparasitic Agent +6

Mutant PfCRT Can Mediate Piperaquine Resistance in African <i>Plasmodium falciparum</i> With Reduced Fitness and Increased Susceptibility to Other Antimalarials

Kathryn J. Wicht, Jennifer L. Small-Saunders, Laura M. Hagenah et al. · The Journal of Infectious Diseases · 2022 · 34 citations · Full text

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

Jennifer L. Small-Saunders, Laura M. Hagenah, Kathryn J. Wicht et al. · PLoS Pathogens · 2022 · 30 citations · Full text

Genetics, Malaria, Parasite Genomics +16

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum

Jennifer L. Small-Saunders, Ameya Sinha, Talia S. Bloxham et al. · Nature Microbiology · 2024 · 26 citations · Full text

Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered <i>Plasmodium falciparum</i> physiology

Laura M. Hagenah, Satish K. Dhingra, Jennifer L. Small-Saunders et al. · mBio · 2023 · 15 citations · Full text