Sigrid Graubner

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

Justin Nussbaum, Stephan Schilling, Holger Cynis et al. · Nature · 2012 · 429 citations · Full text

Life Sciences, Biochemistry, Neuroscience +16

Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated Aβ Is Induced by Pyroglutamate–Aβ Formation

Anca Alexandru, Wolfgang Jagla, Sigrid Graubner et al. · Journal of Neuroscience · 2011 · 103 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Phenotype in 5XFAD Mice

Sadim Jawhar, Oliver Wirths, Stephan Schilling et al. · Journal of Biological Chemistry · 2010 · 102 citations · Full text

Life Sciences, Neurology, Neuroscience +15

The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

Holger Cynis, Torsten Hoffmann, Daniel Friedrich et al. · EMBO Molecular Medicine · 2011 · 91 citations · Full text

Life Sciences, Biochemistry, Immunology +12

Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity

Benedikt Leis, Claudia Held, Fabian Bergkemper et al. · Biotechnology for Biofuels · 2017 · 57 citations · Full text

Life Sciences, Biochemistry, Microbiology +17