Sigrid Graubner

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

Justin Nussbaum, Stephan Schilling, Holger Cynis et al. · Nature · 2012 · 420 citations · Full text

Neurodegenerative Diseases, Biochemistry, Prion-like Behaviour +5

Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated Aβ Is Induced by Pyroglutamate–Aβ Formation

Anca Alexandru, Wolfgang Jagla, Sigrid Graubner et al. · Journal of Neuroscience · 2011 · 101 citations · Full text

Synaptic Transmission, Cell Death, Posttranslational Amyloid-β +22

Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Phenotype in 5XFAD Mice

Sadim Jawhar, Oliver Wirths, Stephan Schilling et al. · Journal of Biological Chemistry · 2010 · 100 citations · Full text

Synaptic Transmission, Neurotransmitter, Psychopharmacology +27

The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

Holger Cynis, Torsten Hoffmann, Daniel Friedrich et al. · EMBO Molecular Medicine · 2011 · 89 citations · Full text

Comparative characterization of all cellulosomal cellulases from Clostridium thermocellum reveals high diversity in endoglucanase product formation essential for complex activity

Benedikt Leis, Claudia Held, Fabian Bergkemper et al. · Biotechnology for Biofuels · 2017 · 57 citations · Full text