Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA

Rong Wang, Kevin R. Braughton, Dorothee Kretschmer, +9

Nature Medicine

Medical MicrobiologyNovel Cytolytic PeptidesHealth SciencesMedicineVirulence Factor +9

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

Dorothee Kretschmer, Anne-Kathrin Gleske, Maren Rautenberg, +11

Cell Host & Microbe

PathogenesisImmunologyReceptor (Biochemistry)Infection ControlNon-peptide Ligand +3

Mobile Genetic Element-Encoded Cytolysin Connects Virulence to Methicillin Resistance in MRSA

Shu Y. Queck, Burhan Khan, Rong Wang, +7

PLoS Pathogens

Molecular BiologyAntibiotic ResistanceBacterial VirulenceDrug ResistanceDisease Resistance +15

Wall teichoic acids mediate increased virulence in Staphylococcus aureus

Stefanie Wanner, Jessica Schade, Daniela Keinhörster, +12

Nature Microbiology

Virulence FactorBacteriologyWall Teichoic AcidsMicrobiologyInfection Control +2

Toll-like receptor 2 activation depends on lipopeptide shedding by bacterial surfactants

Dennis Hanzelmann, Hwang‐Soo Joo, Mirita Franz‐Wachtel, +8

Nature Communications

The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus

Katja Schlatterer, Christian Beck, Dennis Hanzelmann, +8

mBio

Cleavage of Annexin A1 by ADAM10 during Secondary Necrosis Generates a Monocytic “Find-Me” Signal

Karin Blume, Szabolcs Soeroes, Hildegard Keppeler, +5

The Journal of Immunology

ApoptosisImmunologyCell DeathPathologyImmunologic Mechanism +15

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes

Sebastian Blättner, Sudip Das, Kerstin Paprotka, +14

PLoS Pathogens

Microbial PathogensAntibiotic AdjuvantInnate Immune SystemImmunologyBacterial Pathogens +22

<i>Staphylococcus aureus</i> Phenol-Soluble Modulin Peptides Modulate Dendritic Cell Functions and Increase In Vitro Priming of Regulatory T Cells

Jens Schreiner, Dorothee Kretschmer, Juliane Klenk, +7

The Journal of Immunology

Immune ActivationMicrobial PathogensInnate Immune SystemImmune RegulationImmunology +24

Insight into structure‐function relationship in phenol‐soluble modulins using an alanine screen of the phenol‐soluble modulin (PSM) α3 peptide

Gordon Y. C. Cheung, Dorothee Kretschmer, Shu Y. Queck, +9

The FASEB Journal

Microbial PathogensPsmα3 DerivativesPeptide EngineeringMolecular BiologyPeptide Science +22