Samantha Burns

Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization

Daniel K. Whelligan, Savade Solanki, Dawn Taylor et al. · Journal of Medicinal Chemistry · 2010 · 70 citations · Full text

Drug Target, Unusual Inactive Conformation, Kinase Inhibitors +17

Development and evaluation of selective, reversible LSD1 inhibitors derived from fragments

James R. Hitchin, Julian Blagg, Rosemary Burke et al. · MedChemComm · 2013 · 63 citations

Pharmaceutical Science, Drug Target, Peptide Science +20

Structure-Guided Evolution of Potent and Selective CHK1 Inhibitors through Scaffold Morphing

John Reader, Thomas P. Matthews, Suki Klair et al. · Journal of Medicinal Chemistry · 2011 · 59 citations · Full text

Combinatorial Chemistry, Drug Target, Bioorganic Chemistry +18

Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2

Stephen T. Hilton, Sébastien Naud, John Caldwell et al. · Bioorganic & Medicinal Chemistry · 2009 · 57 citations · Full text

Checkpoint Kinase 2, Medicine, Receptor Tyrosine Kinase +6

Identification of Inhibitors of Checkpoint Kinase 1 through Template Screening

Thomas P. Matthews, Suki Klair, Samantha Burns et al. · Journal of Medicinal Chemistry · 2009 · 41 citations · Full text