Concepedia

Pauline Bourbon

PB

Statistics

Publications

11

Citations

876

H-Index

11

Active since

2009

Affiliations

University of Notre Dame(Current)

Collaborative Drug Discovery (United States)

Collaborations Pharmaceuticals (United States)

State Street (United States)

Cornell University

Pauline Bourbon is an author at University of Notre Dame specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

2009–2016

11

Publications

11

Discovery and SAR of 5-(3-Chlorophenylamino)benzo[<i>c</i>][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer

Fabrice Pierre, Peter Chua, Sean O’Brien et al. · Journal of Medicinal Chemistry · 2010 · 299 citations · Full text

, , +15

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

Nina H. Pipalia, Casey C. Cosner, Amy Y. Huang et al. · Proceedings of the National Academy of Sciences · 2011 · 195 citations

, , +17

Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer

Fabrice Pierre, Peter Chua, Sean O’Brien et al. · Molecular and Cellular Biochemistry · 2011 · 155 citations

, , +4

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells

Gemma L. Pearson, Natalie A. Mellett, Kwan Yi Chu et al. · Diabetologia · 2013 · 47 citations · Full text

, , +17

Investigation of <i>N</i>-Aryl-3-alkylidenepyrrolinones as Potential Niemann−Pick Type C Disease Therapeutics

Casey C. Cosner, John T. Markiewicz, Pauline Bourbon et al. · Journal of Medicinal Chemistry · 2009 · 34 citations · Full text

, , +17

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