Gemma L. Pearson

Mitophagy protects β cells from inflammatory damage in diabetes

Vaibhav Sidarala, Gemma L. Pearson, Vishal S. Parekh et al. · JCI Insight · 2020 · 125 citations · Full text

Inflammation, Type 1, Mitophagy +15

Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis

Vaibhav Sidarala, Jie Zhu, Elena Levi-D’Ancona et al. · Nature Communications · 2022 · 82 citations · Full text

Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy

Gemma L. Pearson, Biaoxin Chai, Tracy Vozheiko et al. · Diabetes · 2017 · 78 citations · Full text

Deletion of PKCε Selectively Enhances the Amplifying Pathways of Glucose-Stimulated Insulin Secretion via Increased Lipolysis in Mouse β-Cells

James Cantley, James G. Burchfield, Gemma L. Pearson et al. · Diabetes · 2009 · 52 citations · Full text

Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells

Gemma L. Pearson, Natalie A. Mellett, Kwan Yi Chu et al. · Diabetologia · 2013 · 47 citations

Metabolic Syndrome, Insulin Signaling, Biochemistry +11