Takuma Shikata

Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells.

Hajime Hosoi, Michael B. Dilling, Takuma Shikata et al. · PubMed · 1999 · 316 citations

Apoptosis, Cell Death, Cell Proliferation +23

Studies on the Mechanism of Resistance to Rapamycin in Human Cancer Cells

Hajime Hosoi, Michael B. Dilling, Linda N. Liu et al. · Molecular Pharmacology · 1998 · 172 citations

p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.

Shile Huang, Linda N. Liu, Hajime Hosoi et al. · PubMed · 2001 · 132 citations

Apoptosis, Cell Death, Pathology +20

N-Myc induction stimulated by insulin-like growth factor I through mitogen-activated protein kinase signaling pathway in human neuroblastoma cells.

Akiko Misawa, Hajime Hosoi, A Arimoto et al. · PubMed · 2000 · 43 citations

Developmental Biology, Cell Regulation, Glioma +13

Establishment and characterization of a cisplatin-resistant human neuroblastoma cell line.

Tetsuya Yasuno, Takafumi Matsumura, Takuma Shikata et al. · PubMed · 2000 · 20 citations