Lukas Theo Schmitt

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker et al. · eLife · 2020 · 177 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Rgs16 promotes antitumor CD8 ⁺ T cell exhaustion

Nina Weisshaar, Jingxia Wu, Yanan Ming et al. · Science Immunology · 2022 · 50 citations

Life Sciences, Cancer Biology, Cell Biology +17

The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models

Romain Sigaud, Lisa Rösch, Charlotte Gatzweiler et al. · Neuro-Oncology · 2022 · 49 citations · Full text

Medicine, Oncology, Pharmacology +17

Prediction of designer-recombinases for DNA editing with generative deep learning

Lukas Theo Schmitt, Maciej Paszkowski‐Rogacz, Florian Jug et al. · Nature Communications · 2022 · 45 citations · Full text

Life Sciences, Bioinformatics, Biotechnology +14

Efficient Correction of Oncogenic <i>KRAS</i> and <i>TP53</i> Mutations through CRISPR Base Editing

Shady Sayed, Olga Alexandra Sidorova, Alexander Hennig et al. · Cancer Research · 2022 · 42 citations · Full text

Life Sciences, Genetics, Oncology +16