Romain Sigaud

Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion

Zohra Benyahia, Nadège Dussault, Mylène Cayol et al. · Oncotarget · 2017 · 60 citations · Full text

The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models

Romain Sigaud, Lisa Rösch, Charlotte Gatzweiler et al. · Neuro-Oncology · 2022 · 44 citations · Full text

BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma

Florian Selt, Romain Sigaud, Gintvile Valinciute et al. · Neuro-Oncology · 2022 · 38 citations · Full text

MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas

Romain Sigaud, Thomas Albert, Thomas Hielscher et al. · Nature Communications · 2023 · 35 citations · Full text

A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in <i>BRAF</i> -Driven Pediatric Low-Grade Glioma Cells

Diren Usta, Romain Sigaud, Juliane L. Buhl et al. · Molecular Cancer Therapeutics · 2020 · 26 citations · Full text