Randy J. Chandler

Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy

Randy J. Chandler, Matthew C. LaFave, Gaurav K. Varshney et al. · Journal of Clinical Investigation · 2015 · 380 citations · Full text

Immunology, Pathology, Gene Delivery +18

Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia

An Ding, Jessica L. Schneller, Andrea Frassetto et al. · Cell Reports · 2017 · 249 citations · Full text

Hmut Mrna, Lipid Peroxidation, Immunology +21

Recombinant Adeno-Associated Viral Integration and Genotoxicity: Insights from Animal Models

Randy J. Chandler, Mark S. Sands, Charles P. Venditti · Human Gene Therapy · 2017 · 202 citations · Full text

In Vivo Gene Therapy, Immunology, Clinical Gene Therapy +18

Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype

Rita Sarkar, Renee Tetreault, Guangping Gao et al. · Blood · 2003 · 200 citations · Full text

Mitochondrial dysfunction in <i>mut</i> methylmalonic acidemia

Randy J. Chandler, Patricia M. Zerfas, Sara Shanske et al. · The FASEB Journal · 2008 · 192 citations · Full text