Karen Rooke

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

Alzheimer's Disease, Genetics, Missense Mutation +9

SOD1 mutation is assosiated with accumulation of neurofilaments in amyotrophic lateral scelaries

Guy A. Rouleau, Arthur W. Clark, Karen Rooke et al. · Annals of Neurology · 1996 · 239 citations

Screening for mutations in the open reading frame and promoter of the β-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val→lle

Liana Fidani, Karen Rooke, Marie‐Christine Chartier‐Harlin et al. · Human Molecular Genetics · 1992 · 75 citations

Genetics, Molecular Biology, Disease Gene Identification +17

Analysis of the KSP repeat of the neurofilament heavy subunit in familial amyotrophic lateral sclerosis

Karen Rooke, Denise A. Figlewicz, Fei‐Yu Han et al. · Neurology · 1996 · 74 citations

Neurological Disorder, Genetics, Disease Gene Identification +18