Expert Opinion on Therapeutic Targets

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance

Laura Garros-Regulez, Paula Aldaz, Olatz Arrizabalaga et al. · 2016 · 152 citations · Full text

Medicine, Cancer Biology, Oncology +17

MicroRNA-34a regulates cardiac fibrosis after myocardial infarction by targeting Smad4

Ying Huang, Yuan Qi, Jian-qing Du et al. · 2014 · 141 citations

Life Sciences, Cardiology, Molecular Biology +12

Targeting enzyme inhibitors in drug discovery

Robert A. Copeland, Mark R. Harpel, Peter J. Tummino · 2007 · 130 citations

Life Sciences, Medicinal Chemistry, Pharmacology +14

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

Claudia Bocca, Monica Ievolella, Riccardo Autelli et al. · 2013 · 122 citations · Full text

Medicine, Oncology, Pharmacology +17

Matrix metalloproteinase inhibitors for cancer therapy: the current situation and future prospects

Barbara Fingleton · 2003 · 107 citations

Medicine, Oncology, Pharmacology +13