Resveratrol inhibits TIGAR to promote ROS induced apoptosis and autophagy

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

Meishiang Jang, Lining Cai, George Udeani et al. · Science · 1997 · 4.9K citations

Antiprogression Activity, Oncology, Chemoprevention Strategy +14

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

Ruth Scherz‐Shouval, Elena Shvets, Ephraim Fass et al. · The EMBO Journal · 2007 · 2.1K citations · Full text

Inflammation, Cell Autophagy, Mitophagy +11

TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

Karim Bensaad, Atsushi Tsuruta, Mary Selak et al. · Cell · 2006 · 1.9K citations · Full text

Apoptosis, Cell Death, P53-inducible Regulator +3

Inhibition of Macroautophagy Triggers Apoptosis

Patricia Boya, Rosa A. González‐Polo, Noëlia Casares et al. · Molecular and Cellular Biology · 2005 · 1.6K citations · Full text

SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

Hiyaa S. Ghosh, Michael W. McBurney, Paul D. Robbins · PLoS ONE · 2010 · 394 citations · Full text

Caloric Restriction, Reductive Stress, Mammalian Target +14