Journal of the American Medical Informatics Association · 2013 · 24 citations · 12 references
Family MedicineData RepositoryOutcomes Research CapacityResearch EvaluationData PublishingData ScienceData IntegrationPublic HealthData ManagementHealth Services ResearchHealth PolicyOutcomes ResearchResearch-practice PartnershipUrology DepartmentResearch Data ManagementResearch Data ArchivingClinical DataNew Research ModelCase ReportMedicineHealth Informatics
This paper describes our considerations and methods for implementing an open-source centralized research data repository (CRDR) and reports its impact on retrospective outcomes research capacity in the urology department at Columbia University. We performed retrospective pretest and post-test analyses of user acceptance, workflow efficiency, and publication quantity and quality (measured by journal impact factor) before and after the implementation. The CRDR transformed the research workflow and enabled a new research model. During the pre- and post-test periods, the department's average annual retrospective study publication rate was 11.5 and 25.6, respectively; the average publication impact score was 1.7 and 3.1, respectively. The new model was adopted by 62.5% (5/8) of the clinical scientists within the department. Additionally, four basic science researchers outside the department took advantage of the implemented model. The average proximate time required to complete a retrospective study decreased from 12 months before the implementation to <6 months after the implementation. Implementing a CRDR appears to be effective in enhancing the outcomes research capacity for one academic department.
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Paul A. Harris, Robert Taylor, Robert J. Thielke et al. · Journal of Biomedical Informatics · 2008 · 48.8K citations · Full text
Bias and causal associations in observational research
David A. Grimes, Kenneth F. Schulz · The Lancet · 2002 · 1.5K citations