Europe PMC (PubMed Central) · 2009 · 455 citations · 0 references
Life SciencesBiochemistryMolecular BiologyCarbohydrate BiochemistryGlycobiologyMetabolismExtracellular Matrix GlycansGlycan BiosynthesisGlycan StructureGlycosylation PathwaysPolysaccharide FunctionPolysaccharide StructureExtracellular Matrix ProteoglycansGlycosaminoglycan StructureGlycosaminoglycansProteoglycan BiosynthesisProteoglycan Core StructureProteoglycan MetabolismProteoglycan StructureProteoglycans
This chapter focuses on the structure, biosynthesis, and general biology of proteoglycans. Topics include a description of the major families of proteoglycans, their characteristic polysaccharide chains (glycosaminoglycans), biosynthetic pathways, and general concepts about proteoglycan function. Proteoglycans, like other glycoconjugates, are enormously diverse and have many essential roles in biology.