Intermediary carbohydrate metabolism

Abstract

THE keystone of a theory of intermediary carbohydrate metabolism, put forward by Dakin and Dudley [1913, 3; 1914] is the ketonic aldehyde, methyl- glyoxal. The postulation of this substance as the catabolic precursor and anabolic successor of lactic acid (CH3. CO. CO = CH3. CHOH. COOH) corre- lates in an intelligible scheme many of the known metabolic changes of carbohydrates.