Studies on Stachys sieboldii MIQ. II. Anti-anoxia Action and the Active Constituents

Johji Yamahara, Tetsuya Kitani, Hiromi Kobayashi, Yuzo Kawahara

YAKUGAKU ZASSHI · 1990 · 59 citations · 0 references

DOIFull text

Open access

Concepts

Abstract

During screening for the development of drugs from natural products, methanolic extract of tuber of Stachys sieboldii MIQ. (Labiatae) significantly inhibited the lethal induced by KCN in mice. The methanolic extract was fractionated by column chromatography to identify the active constituents. Acteoside and stachysoside C, phenylethanoid glycoside, have a significant effect on the KCN-induced anoxia model.