YAKUGAKU ZASSHI · 1990 · 59 citations · 0 references
MedicineBiochemistryPharmacologyBiochemical PharmacologyExperimental PharmacologyPharmacodynamicsEnzyme InhibitionIn Vitro PharmacologyMechanisms Of Drug ActionMedicinal PlantsBioactive ConstituentsColumn ChromatographyGlycoside Natural ProductsMedicinal UsesPharmacological ScreeningToxicity Of Medicinal Plants
During screening for the development of drugs from natural products, methanolic extract of tuber of Stachys sieboldii MIQ. (Labiatae) significantly inhibited the lethal induced by KCN in mice. The methanolic extract was fractionated by column chromatography to identify the active constituents. Acteoside and stachysoside C, phenylethanoid glycoside, have a significant effect on the KCN-induced anoxia model.