Extent and Patterns of Adaptation of Enzyme Activities in Livers of Normal Rats Fed Diets High in Glucose and Fructose

Abstract

Earlier reports (1,2) showed that the activities of four hepatic enzymes involved in the utilization of glucose 6-phosphate were altered, some of them dramatically, simply by substitution of diets rich in free hexoses (glucose or fructose) for a stock diet devoid of them.The adaptation by four enzymes led us to explore the extent and nature of the adjustment.