Potential of Immobilized Artificial Membranes for Predicting Drug Penetration Across the Blood−Brain Barrier

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

Victor A. Levin · Journal of Medicinal Chemistry · 1980 · 814 citations

Medicine, Pharmacology, Physiology +14

Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists

Rodney C. Young, Robert Cameron Mitchell, Thomas H. Brown et al. · Journal of Medicinal Chemistry · 1988 · 522 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Transport of Steroid Hormones through the Rat Blood-Brain Barrier

William M. Pardridge, Lawrence J. Mietus · Journal of Clinical Investigation · 1979 · 442 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Transport of small molecules through the blood-brain barrier: biology and methodology

William M. Pardridge · Advanced Drug Delivery Reviews · 1995 · 274 citations

Medicine, Neuroscience, Pharmacology +14

A method to determine the ability of drugs to diffuse through the blood-brain barrier.

Alina H. Seelig, Rudolf Gottschlich, Ralf Devant · Proceedings of the National Academy of Sciences · 1994 · 195 citations

Pharmacy, Pharmaceutics, Pharmacology +17