A novel transflectance near infrared spectroscopy technique for monitoring hot melt extrusion

Near-infrared spectroscopy applications in pharmaceutical analysis

J. Luypaert, D.L. Massart, Yvan Vander Heyden · Talanta · 2006 · 421 citations

Spectroscopic Method, Medicine, Spectroscopy +9

Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion

Michael M. Crowley, Britta Schroeder, Anke Fredersdorf et al. · International Journal of Pharmaceutics · 2003 · 254 citations

Engineering, Polymer Science, Micro-encapsulation +7

Propagation of measurement errors for the validation of predictions obtained by principal component regression and partial least squares

Klaas Faber, Bruce R. Kowalski · Journal of Chemometrics · 1997 · 233 citations

Parameter Estimation, Engineering, Classical Regression Model +21

Evaluation of hot-melt extrusion as a new technique for the production of polymer-based pellets for sustained release capsules containing high loadings of freely soluble drugs

Nicolas Follonier, Éric Doelker, Ewart T. Cole · Drug Development and Industrial Pharmacy · 1994 · 167 citations

Engineering, Sustained Release Capsules, Dosage Form +17

Raman spectroscopy for the in-line polymer–drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process

Lien Saerens, L. Dierickx, Bruno Lenain et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2010 · 149 citations · Full text

Materials Science, Engineering, In-line Polymer–drug Quantification +14