IL-6 promoter polymorphism at position -174 modulates the phenotypic expression of polymyalgia rheumatica in biopsy-proven giant cell arteritis.

Miguel Á. González‐Gay, Ali H. Hajeer, Adèle Dababneh, Carlos García‐Porrúa, Derek L. Mattey, Mahsa M. Amoli, Wendy Thomson, Wer Ollier

PubMed · 2003 · 66 citations · 0 references

Abstract

Allele C at position -174 in the 5' promoter region of the IL-6 gene may be associated with PMR in biopsy-proven GCA patients not carrying HLA-DRBI *04 alleles.