PubMed · 2010 · 19 citations · 5 references
Veterinary MedicineAnesthesiologyPediatric DentistryAnesthesiaGeneral AnesthesiaLocal AnesthesiaAnesthesia For Dental ProceduresAnesthesia For Oral SurgeryDental Local AnesthesiaPediatric AnesthesiaPediatric Dental AnesthesiaComprehensive Dental RehabilitationGeneral Anesthesia In ChildrenLocal Anesthetic TherapyOutpatient Dental AnesthesiaOutpatient Pediatric SurgeryPediatric Local AnesthesiaPerioperative Local AnesthesiaVital Sign Analysis
PURPOSE: The purpose of this study was to evaluate the use of intraoperative local anesthetics in pediatric outpatient dental surgery. This study assessed physiologic stability, as defined by fluctuations in end-tidol carbon dioxide, heart rate, and respiratory rate, as well as subsequent anesthesiologist intervention. METHODS: Forty-eight children (mean age = 3.87 years [+/- l.06 SD]) were included in this randomized, parallel-design study. Intervention variables and the research design were validated in a pilot study. Following collection of baseline vital signs, patients were either given local anesthesia before comprehensive dental treatment or not. Vital sign change was recorded 30 seconds after each procedure. RESULTS: In the no local anesthetic group, 2 areas were found to be statistically significant: (1) postextraction end-tidal carbon dioxide; and (2) heart rate. There was a statistically significant relationship between local anesthetic use and anesthesiologist intervention when assessing the pooled data (P = .001). CONCLUSION: Patients who were not given intraoperative local anesthesia were more likely to experience vital sign fluctuation requiring anesthesiologist intervention.
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Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma
Yuan Chang, Ethel Cesarman, Melissa S. Pessin et al. · Science · 1994 · 5.7K citations
David C. McGiffin, Timo Savunen, James K. Kirklin et al. · Journal of Thoracic and Cardiovascular Surgery · 1995 · 64 citations · Full text
Medicine, Cardiology, Surgery +17