Lithium-induced enlargement of a lingual thyroid.

N. Talwar, Sumit Mohan, Bina Ravi, M Andley, A Kumar

PubMed · 2008 · 23 citations · 0 references

Concepts

Abstract

Lingual thyroid is a rare developmental anomaly. It is the result of failure of the thyroid to descend from the foramen caecum to its prelaryngeal site. Lithium is a known goitrogen, but has never been reported to cause symptomatic enlargement of the lingual thyroid. We describe a 40-year-old woman, who presented with a foreign body sensation and progressive dysphagia caused by an ectopic lingual thyroid tissue measuring 4 cm x 3 cm x 3.5 cm. She had been taking lithium for treatment of bipolar disorder and had hypothyroidism. Her symptoms were relieved after excision of the ectopic thyroid tissue.