Anti-inflammatory effects of noradrenaline on LPS-treated microglial cells: Suppression of NFκB nuclear translocation and subsequent STAT1 phosphorylation

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

Natural Sciences, Rna Splicing, Rna Biology +9

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.

Charles J. Lowenstein, Evan Alley, Pravin Raval et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

Innate Immune System, Immunology, Synthase Gene +24

Neuronal Loss Is Greater in the Locus Coeruleus Than Nucleus Basalis and Substantia Nigra in Alzheimer and Parkinson Diseases

Chris Zarow, Scott A. Lyness, James A. Mortimer et al. · Archives of Neurology · 2003 · 985 citations

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

Michael T. Heneka, Fabian Nadrigny, Tommy Regen et al. · Proceedings of the National Academy of Sciences · 2010 · 512 citations · Full text

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

Dmitry Guschin, Neil C. Rogers, James Briscoe et al. · The EMBO Journal · 1995 · 433 citations · Full text

Inflammation, Cytokine, Signal Transduction +10