FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription

A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon et al. · Science · 2007 · 4.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

Guifang Jia, Ye Fu, Xu Zhao et al. · Nature Chemical Biology · 2011 · 4.1K citations

Life Sciences, Genetics, Molecular Biology +11

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Seung Hee Yoo, Shin Yamazaki, Phillip L. Lowrey et al. · Proceedings of the National Academy of Sciences · 2004 · 2.4K citations · Full text

Nursing, Neuroscience, Physiology +17

The Obesity-Associated <i>FTO</i> Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Thomas Gerken, Christophe A. Girard, Yi‐Chun Loraine Tung et al. · Science · 2007 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

Gad Asher, David Gatfield, Markus Stratmann et al. · Cell · 2008 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +12