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The Use of N-Acetylcysteine in Intensive Care

Megan Atkinson

Critical Care and Resuscitation · 2002 · 47 citations · 33 references

DOIFull text

Open access

Abstract

N-acetylcysteine has antioxidant properties that may be useful in many clinical conditions. Currently, however, it can only be recommended as therapy for paracetamol poisoning, in all other disorders it is still under evaluation.

References

33

Prevention of Radiographic-Contrast-Agent–Induced Reductions in Renal Function by Acetylcysteine

Martin Tepel, Markus van der Giet, Carola Schwarzfeld et al. · New England Journal of Medicine · 2000 · 1.6K citations · Full text

Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.

L. F. Prescott, R. N. Illingworth, Julia Critchley et al. · BMJ · 1979 · 658 citations · Full text

, , +14

Improvement by Acetylcysteine of Hemodynamics and Oxygen Transport in Fulminant Hepatic Failure

Phillip Harrison, Julia Wendon, Alexander Gimson et al. · New England Journal of Medicine · 1991 · 592 citations · Full text

Acetaminophen‐induced hepatic injury: Protective role of glutathione in man and rationale for therapy

Jerry R. Mitchell, Snorri S. Thorgeirsson, William Z. Potter et al. · Clinical Pharmacology & Therapeutics · 1974 · 531 citations

, , +18

Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial.

Richard Keays, Philip M. Harrison, Julia Wendon et al. · BMJ · 1991 · 485 citations · Full text