Murine Macrophages Cultured with IL-4 Acquire a Phenotype Similar to That of Epithelioid Cells from Granulomatous Inflammation

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

The granulomatous inflammatory response. A review.

Adams Do · PubMed · 1976 · 552 citations · Full text

Veterinary Medicine, Immunology, Pathology +12

TRANSFORMATION OF MONOCYTES IN TISSUE CULTURE INTO MACROPHAGES, EPITHELIOID CELLS, AND MULTINUCLEATED GIANT CELLS

Jerry S. Sutton, Leon Weiss · The Journal of Cell Biology · 1966 · 446 citations · Full text

Life Sciences, Cell Biology, Immunology +14

Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells.

A K McNally, James M. Anderson · PubMed · 1995 · 299 citations

Life Sciences, Cell Biology, Immunology +17

In vitro differentiation of human monocytes. Differences in monocyte phenotypes induced by cultivation on glass or on collagen.

Gilla Kaplan, Gustav Gaudernack · The Journal of Experimental Medicine · 1982 · 223 citations · Full text

Life Sciences, Cell Biology, Immunology +13