Concepedia

Prediction of Membrane Permeability to Peptides from Calculated Dynamic Molecular Surface Properties

Patric Stenberg, Kristina Luthman, Per Artursson

Pharmaceutical Research · 1999 · 83 citations · 24 references

DOI

Concepts

References

24

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

, , +16

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

F. MOHAMADI, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry · 1990 · 3.8K citations

, , +13

Linear solvation energy relationships. 23. A comprehensive collection of the solvatochromic parameters, .pi.*, .alpha., and .beta., and some methods for simplifying the generalized solvatochromic equation

Mortimer J. Kamlet, J.‐L. M. Abboud, Michael H. Abraham et al. · The Journal of Organic Chemistry · 1983 · 3.6K citations

, , +14

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

, , +16

An internal-coordinate Monte Carlo method for searching conformational space

George Chang, Wayne C. Guida, W. Clark Still · Journal of the American Chemical Society · 1989 · 1.1K citations

, , +9