Association of polymorphisms in the ?2-adrenergic receptor gene with obesity, hypertriglyceridaemia, and diabetes mellitus (Short Communication)

Amino-Terminal Polymorphisms of the Human .beta.2-Adrenergic Receptor Impart Distinct Agonist-Promoted Regulatory Properties

Stuart A. Green, Michael A. Innis, Stephen B. Liggett · Biochemistry · 1994 · 775 citations

Medicine, Molecular Biology, Pharmacology +17

Mutations in the Gene Encoding for the <i>β</i> 2-adrenergic Receptor in Normal and Asthmatic Subjects

Ellen Reihsaus, Michael A. Innis, Neil R. MacIntyre et al. · American Journal of Respiratory Cell and Molecular Biology · 1993 · 622 citations

Life Sciences, Genetics, Molecular Genetics +13

Genetic Variation in the β₃-Adrenergic Receptor and an Increased Capacity to Gain Weight in Patients with Morbid Obesity

Karine Clément, Christian Vaisse, Brian S. Manning et al. · New England Journal of Medicine · 1995 · 617 citations

Life Sciences, Genetics, Molecular Genetics +16

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.

V. Large, L Hellström, S Reynisdottir et al. · Journal of Clinical Investigation · 1997 · 418 citations · Full text

Medicine, Endocrinology, Molecular Genetics +15

A Mutation in the β3-Adrenergic Receptor Gene Is Associated with Obesity and Hyperinsulinemia in Japanese Subjects

Hiroaki Kadowaki, Koichiro Yasuda, K Iwamoto et al. · Biochemical and Biophysical Research Communications · 1995 · 216 citations · Full text

Medicine, Endocrinology, Genetics +15