Concepedia

Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells.

Zhuo Chen, De‐Quan Li, Louis Tong, Paul A. Stewart, Claire Chu, Stephen C. Pflugfelder

PubMed · 2006 · 31 citations · 36 references

Abstract

These findings demonstrate that TGF-beta1 and/or TGF-beta2 inhibit proliferation of primary cultured human limbal epithelial cells and that p57 and p15 play roles in this process.

References

36

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 54.9K citations

, , +11

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.1K citations

, , +9

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

, , +9

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Kornélia Polyák, Jun‐ya Kato, Michael J. Solomon et al. · Genes & Development · 1994 · 2K citations · Full text

, , +17

pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest

Gregory J. Hannon, David Beach · Nature · 1994 · 1.9K citations

, , +7