Concepedia

Development and validation of a bioanalytical method for the simultaneous determination of heroin, its main metabolites, naloxone and naltrexone by LC–MS/MS in human plasma samples: Application to a clinical trial of oral administration of a heroin/naloxone formulation

Raquel Moreno-Vicente, Zuriñe Fernández-Nieva, Arantza Navarro, Irene Gascón-Crespí, Magí Farré-Albaladejo, M. Igartua, Rosa Marı́a Hernández

Journal of Pharmaceutical and Biomedical Analysis · 2015 · 19 citations · 25 references

DOI

Concepts

References

25

The Pharmacokinetics of Heroin in Patients with Chronic Pain

Charles E. Inturrisi, Mitchell B. Max, Kathleen M. Foley et al. · New England Journal of Medicine · 1984 · 243 citations

, , +12

Treatment of opioid-induced constipation with oral naloxone: A pilot study

Joan Culpepper-Morgan, Charles E. Inturrisi, Russell K. Portenoy et al. · Clinical Pharmacology & Therapeutics · 1992 · 209 citations

, , +17

Low-Dose Oral Naloxone Reverses Opioid-Induced Constipation and Analgesia

Maywin Liu, Eric Wittbrodt · Journal of Pain and Symptom Management · 2002 · 205 citations

, , +10

The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry

Elisabeth J. Rook, M. J. X. Hillebrand, Hilde Rosing et al. · Journal of Chromatography B · 2005 · 136 citations

, , +17

HUMAN ERYTHROCYTE BUT NOT BRAIN ACETYLCHOLINESTERASE HYDROLYSES HEROIN TO MORPHINE

Asher Salmon, Zafrir Goren, Yaniv Y. Avissar et al. · Clinical and Experimental Pharmacology and Physiology · 1999 · 81 citations

, , +16