Substance UsePsychopharmacologyAlcohol MisuseAddiction MedicinePsychoactive Substance UseNeurologySevere ManifestationsHealth SciencesPsychoactive DrugPsychiatryHeavy DrinkersNeuropharmacologyAlcohol AbuseAlcohol ControlAlcohol DependenceSubstance AbuseAlcohol StudiesAddictionAlcohol ConsumptionMedicinePsychopathology
Heavy drinkers who suddenly decrease their alcohol consumption or abstain completely may experience alcohol withdrawal (AW). Signs and symptoms of AW can include, among others, mild to moderate tremors, irritability, anxiety, or agitation. The most severe manifestations of withdrawal include delirium tremens, hallucinations, and seizures. These manifestations result from alcohol-induced imbalances in the brain chemistry that cause excessive neuronal activity if the alcohol is withheld. Management of AW includes thorough assessment of the severity of the patient's symptoms and of any complicating conditions as well as treatment of the withdrawal symptoms with pharmacological and nonpharmacological approaches. Treatment can occur in both inpatient and outpatient settings. Recognition and treatment of withdrawal can represent a first step in the patient's recovery process.
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Pharmacological Management of Alcohol Withdrawal
Michael F. Mayo‐Smith · JAMA · 1997 · 757 citations
Individualized Treatment for Alcohol Withdrawal
Richard Saitz · JAMA · 1994 · 357 citations
The effect of alcohol on the nervous system.
M Víctor, Raymond D. Adams · PubMed · 1953 · 282 citations