Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines

An Orally Available Small-Molecule Inhibitor of c-Met, PF-2341066, Exhibits Cytoreductive Antitumor Efficacy through Antiproliferative and Antiangiogenic Mechanisms

Helen Y. Zou, Qiuhua Li, Joseph H. Lee et al. · Cancer Research · 2007 · 750 citations · Full text

Medicine, Medicinal Chemistry, Oncology +16

Antitumor Activity of a Small-Molecule Inhibitor of Human Silent Information Regulator 2 Enzymes

Birgit Heltweg, Tonibelle Gatbonton, Aaron D. Schuler et al. · Cancer Research · 2006 · 464 citations

Medicine, Oncology, Pharmacology +17

Celecoxib Induces Apoptosis by Inhibiting 3-Phosphoinositide-dependent Protein Kinase-1 Activity in the Human Colon Cancer HT-29 Cell Line

Sébastien Arico, Sophie Pattingre, Chantal Bauvy et al. · Journal of Biological Chemistry · 2002 · 300 citations · Full text

Medicine, Oncology, Pharmacology +17

Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells

Yong Xia, Chuandong Fan, Bao‐Xiang Zhao et al. · European Journal of Medicinal Chemistry · 2008 · 202 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

Jean Berthelet, Laurence Dubrez · Cells · 2013 · 174 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15